{"product_id":"blueberry-extact","title":"Blueberry Extract","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003eThe Brain is the center of our personal universe, controlling and effecting all the systems in the body, including motor functions (balance, strength or frailty), immunity, and of course, how we think. Foggy brain, memory lapses, and cognitive decline are effecting the old and young populations alike.\u003c\/p\u003e\n\u003cp\u003eScientists describe blueberries’ polyphenols as essential agents of neuro-regeneration and repair. Research studies show that a daily intake of at least 1 cup of blueberries offer important regenerative support for a healthy brain.*\u003c\/p\u003e\n\u003cp\u003eThe Blueberry Extract is potent: It takes 80 pounds of blueberries to get one pound of the pure purple extract. One capsule of the polyphenolic extract is equivalent to a cup and a quarter of whole blueberries!*\u003c\/p\u003e\n\u003cp\u003eOur Blueberry Extract stands alone. 100% North American blueberry extract (\u003cem\u003eVaccinium corymbosum\u003c\/em\u003e) provides a daily comprehensive profile of polyphenols to feed your brain.*\u003c\/p\u003e\n\u003cp\u003eThe Blueberry Extract is Pure, Vegan, Kosher, and Non GMO.\u003c\/p\u003e\n\u003ch6\u003eDescription \u003c\/h6\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003eThe\u003cspan\u003e \u003c\/span\u003e\u003cem\u003e\u003cstrong\u003eBlueberry Extract\u003c\/strong\u003e\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eoffers the highest concentration of the North American blueberry species,\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eVaccinium corymbosum\u003c\/em\u003e, with a significant broad-spectrum phenolic profile.\u003c\/p\u003e\n\u003cp\u003eThe\u003cspan\u003e \u003c\/span\u003e\u003cem\u003e\u003cstrong\u003eBlueberry Extract\u003c\/strong\u003e\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eis a powerful concentration of anthocyanins: It takes eighty pounds of blueberries to get one pound of the pure purple extract. This means that one capsule of the extract is equivalent to a cup and a quarter of whole blueberries.\u003c\/p\u003e\n\u003cp\u003eEach vegan capsule has 500mg of the pure extract, without any excipients or fillers.\u003c\/p\u003e\n\u003cp\u003eTuft University’s James Joseph and Barbara Shukitt-Hale have researched the use and application of blueberries as a potential therapeutic agent for many years. Their studies along with their colleagues demonstrate that blueberries and blueberry extract reverse and prevent brain aging (Shukitt-Hale et al., 2008; 2007), improve memory and motor skills (Carey et al., 2014; Malin et al., 2011; Brewer et al., 2010), repair neuronal tissue and function (Joseph et al., 2003; Miller et al., 2012), and serve as a potent anti-aging food (Joseph et al., 1999; 2009; Shukitt-Hale et al., 2015; 2012).*\u003c\/p\u003e\n\u003cp\u003eThe\u003cspan\u003e \u003c\/span\u003e\u003cem\u003e\u003cstrong\u003eBlueberry Extract\u003c\/strong\u003e\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003ewas designed with Dr. Joseph’s assistance by converting some of the data from his research to human consumption.*\u003c\/p\u003e\n\u003cp\u003eSteward, Sridhar, and Meyer (2013) define regeneration of the nerves as a process of repairing or replacing nerve cells that have been damaged. Studies have hypothesized that an antioxidant-enriched diet may affect neuro-regeneration and inhibit inflammation due to their high anthocyanins (Szajdek \u0026amp; Borowska, 2008; Sweeney et al., 2002).*\u003c\/p\u003e\n\u003cp\u003eResearch studies and reviews by Latif (2015), Panickar \u0026amp; Anderson (2010), Subash et al. (2014), Panickar (2013), Schaffer et al. (2006), and Letenneur et al. (2007), demonstrate the great ability of flavonoids to offer a consistent neuro-protective nutriceutical.\u003c\/p\u003e\n\u003cp\u003eStratheam et al. (2014) demonstrate that anthocyanin rich extracts of blueberries and grape seed support the process of neuro re-generation by interfering with the neurotoxin, rotenone, and improving the mitochondrial function. Gao et al. (2012) find that a habitual intake of dietary flavonoids is associated with a lower risk of developing neurological issues, such as Parkinson, or lessening brain edema (Panickar \u0026amp; Anderson, 2010). Kovacsova et al. (2010) researched the biochemical pathways and molecular neuro-protective mechanisms of polyphenols in the brain. Antioxidant activity reduces neuro-inflammation and supports the prevention of neuro-degeneration (Stromberg et al., 2005). Williams \u0026amp; Spencer (2012) and Galli et al. (2006) show that a blueberry-supplemented diet reverses age-related declines with improved cognition and nerve regeneration.*\u003c\/p\u003e\n\u003cp\u003eThe process of neurological regenerative ability of blueberries is linked to their potent anti-inflammatory and antioxidant properties (Subash et al., 2014; Duffy et al., 2008; Shukitt-Hale et al., 2008), effecting the reduction of NF Kappa beta, Cox-2 and Isoprostane (Youdim et al., 2002). For this reason, studies emphasize the important dietary role of blueberries, as anthocyanins are able to reduce oxidative stress and anti-inflammatory cytokines (McAnulty et al., 2011).*\u003c\/p\u003e\n\u003cp\u003eDue to their high levels of anthocyanins, blueberries are also shown in research to contribute to heart health (McAnulty, 2014; Louis et al., 2014; Erlund et al., 2008; Youdim \u0026amp; Joseph, 2001).*\u003c\/p\u003e\n\u003cp\u003eHow available are these anthocyanins? Mazza et al. (2002) has demonstrated that consumption of blueberries raises blood serum ORAC (antioxidant capacity). Emerging evidence confirms the ability of the human body to absorb anthocyanins, demonstrating a greater bioavailability (Bell et al., 2015), prolonged circulation, and relatively high concentration of anthocyanins metabolites (Lila et al., 2016).*\u003c\/p\u003e\n\u003cp\u003eSee the Research tab for additional bibliography to further understand the application and use of blueberry and blueberry extract.\u003c\/p\u003e\n\u003cp\u003e*These statements have not been evaluated by the Food \u0026amp; Drug Administration. This products is not intended to diagnose, treat, cure or prevent any disease. The information and citations of research are for informational purposes only. Please be sure to consult your health care provider before taking this or any other product.\u003c\/p\u003e\n\u003ch5\u003e\u003cstrong\u003eREFERENCES\u003c\/strong\u003e\u003c\/h5\u003e\n\u003cp\u003eErlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P… Jula, A. (2008). Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eAm J Clin Nutr 87\u003c\/em\u003e, 323-331.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/ajcn.nutrition.org\/content\/87\/2\/323.short\"\u003eArticle\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eGalli, R.L., Bielinski, D.F., Szprengiel, A., Shukitt-Hale, B., Joseph, J.A. (2006). Blueberry supplemented diet reverses age-related decline in hippocampal HSP70 neuroprotection.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNeurobio Aging, 27\u003c\/em\u003e, 344-350. DOI:\u003ca href=\"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2005.01.017\"\u003e10.1016\/j.neurobiolaging.2005.01.017\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eGao, X., Cassidy, A., Schwarzschild, M.A., Rimm, E.B., \u0026amp; Ascherio, A. (2012). Habitual intake of dietary flavonoids and risk of Parkinson disease.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNeurology, 78\u003c\/em\u003e(10), 1138-45. doi:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/dx.doi.org\/10.1212%2FWNL.0b013e31824f7fc4\"\u003e10.1212\/WNL.0b013e31824f7fc4\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eJoseph, J., Cole, G., Head, E., Ingram, D. (2009). Nutrition, brain aging, and neurodegeneration.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eJ. Neurosci.\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003e29(41), 12795–12801. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1523\/JNEUROSCI.3520-09.2009\"\u003e10.1523\/JNEUROSCI.3520-09.2009\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eJoseph, J.A., Shukitt-Hale, B., \u0026amp; Lau, F.C. (2007). Fruit polyphenols and their effects on neuronal signaling and behavior in senescence\u003cspan\u003e \u003c\/span\u003e\u003cem\u003e.\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003e\u003cem\u003eAnn NY Acd Sci\u003c\/em\u003e\u003cem\u003e, 1100,\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003e470-85\u003cem\u003e.\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003eDOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1196\/annals.1395.052\"\u003e10.1196\/annals.1395.052\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eJoseph, J.A., Denisova, N.A., Arendash, G., Gordon, M., Diamond, D., Shukitt-Hale, B., Morgan, D. (2003). Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNutr Neurosci, 6\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003e(3), 153-162. DOI:\u003ca href=\"https:\/\/doi.org\/10.1080\/1028415031000111282\"\u003e10.1080\/1028415031000111282\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eJoseph, J.A., Shukitt-Hale, B., Denisova, N.A., Bielinski, D., Martin, A., McEwen, J.J., \u0026amp; Bickford, P.C. (1999). Reversals of age-related declines in neuronal signal\u003c\/p\u003e\n\u003cp\u003eJoseph, J., Cole, G., Head, E., Ingram, D. (2009). Nutrition, brain aging, and neurodegeneration.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eJ. Neurosci.\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003e29(41), 12795–12801. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1523\/JNEUROSCI.3520-09.2009\"\u003e10.1523\/JNEUROSCI.3520-09.2009\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eKovacsova, M., Barta, A., Parohova, J., Vrankova, S., Pechanova, O. (2010). Neuroprotective mechanisms of natural polyphenolic compounds.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eAct Nerv Super Rediviva, 52\u003c\/em\u003e, 181-186.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/www.researchgate.net\/publication\/228471226_Neuroprotective_Mechanisms_of_Natural_Polyphenolic_Compounds\"\u003eAbstract\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eLatif, R. (2015). Flavonoids as novel neuroprotective nutraceuticals.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eSaudi J Health Sci, 4\u003c\/em\u003e, 1-4.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/www.saudijhealthsci.org\/article.asp?issn=2278-0521;year=2015;volume=4;issue=1;spage=1;epage=4;aulast=Latif;type=3\"\u003eDOI:10.4103\/2278-0521.151402\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eMcAnulty, L.S. Nieman, D.C., Dumke, C.L., Shooter, L.A., Henson, D.A., Utter, A.C., … McAnulty, S.R. (2011). Effect of blueberry ingestion on natural killer cell counts, oxidative stress, and inflammation prior to and after 2.5 h of running.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eAppl Physio Nutr Metab\u003c\/em\u003e, 36(6), 976-84. DOI:\u003ca href=\"https:\/\/doi.org\/10.1139\/h11-120\"\u003e10.1139\/h11-120\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003ePanickar, K.S., \u0026amp; Jang, S. (2013). Dietary and plant polyphenols exert neuroprotective effects and improve cognitive function in cerebral ischemia.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eRecent Pat Food Nutr Agric, 5(\u003c\/em\u003e2), 128-43. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/www.eurekaselect.com\/110867\/article\"\u003e10.2174\/1876142911305020003\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSchaffer, S., Eckert, G.P., Schmitt-Schilling, S., \u0026amp; Muller, W.E. (2006). Plant foods and brain aging: a critical appraisal.\u003cem\u003eForum Nutr, 59\u003c\/em\u003e, 86-115. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1159\/000095209\"\u003e10.1159\/000095209\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eShukitt-Hale, B., Bielinski, D.F., Lau, F.C., Willis, L.M., Carey, A.N., \u0026amp; Joseph, J.A. (2015). The beneficial effects of berries on cognition, motor behaviour and neuronal function in ageing.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eBr J Nutr, 114\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003e(10), 1542-9.DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1017\/S0007114515003451\"\u003e10.1017\/S0007114515003451\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eShukitt-Hale, B. (2012). Blueberries and neuronal aging.\u003cem\u003eGerontology\u003c\/em\u003e,\u003cspan\u003e \u003c\/span\u003e\u003cem\u003e58\u003c\/em\u003e, 518-523. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1159\/000341101\"\u003e10.1159\/000341101\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eShukitt-Hale, B., Lau, F.C., Joseph, J.A. (2008). Berry fruit supplementation and the aging brain.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eJournal of Agricultural and Food Chemistry\u003c\/em\u003e\u003cem\u003e,\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003e\u003cem\u003e56\u003c\/em\u003e, 636–641. DOI\u003ca href=\"https:\/\/doi.org\/10.1021\/jf072505f\"\u003e10.1021\/jf072505f\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eShukitt-Hale, B., Carey, A.N., Jenkins, D., Rabin, B.M., Joseph, J.A. (2007). Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNeurobiol Aging, 28\u003c\/em\u003e, 1187-1194. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2006.05.031\"\u003e10.1016\/j.neurobiolaging.2006.05.031\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSteward, M.N., Sridhar, A., \u0026amp; Meyer, J.S. (2013). Neural regeneration. Curr Top Microbiol Immunol, 367, 163-91. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1007\/82_2012_302\"\u003e10.1007\/82_2012_302\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eStrathearm, K.D., Yousef, G.G., Grace, M.H., Tambe, M.A., Ferruzzi, M.G., Wu, Q.L., Simon, J.E., Lila, M.A., \u0026amp; Rochet, J.C. (2014). Neuroprotective effects of anthocyanin-and proanthocyanidin-rich extracts in cellular models of Parkinson’s diseases.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eBrain Res\u003c\/em\u003e, 1555, 60-77. . DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.brainres.2014.01.047\"\u003e10.1016\/j.brainres.2014.01.047\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSubash, S., Essa, M.M., Al-Adwi, S., Memon, M.A., Manivasagan, T., \u0026amp; Akbar, M. (2014). Neuroprotective effects of berry fruits on neurodegenerative diseases.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNeural Regeneration Research\u003c\/em\u003e, 9(16), 1557-1566. .\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/www.nrronline.org\/article.asp?issn=1673-5374;year=2014;volume=9;issue=16;spage=1557;epage=1566;aulast=Subash\"\u003eDOI:10.4103\/1673-5374.139483\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSweeney, M.I., Kalt, W., MacKinnon, S.L., Ashby, J., Gottschall-Pass, K.T. (2002) Feeding rats diets enriched in lowbush blueberries for six weeks decreases ischemia-induced brain damage.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNutr Neurosci 5\u003c\/em\u003e, 427- 431. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1080\/1028415021000055970\"\u003e10.1080\/1028415021000055970\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eYoudim, K.A., Joseph, J.A. (2001). A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eFree Radic Biol Med, 30\u003c\/em\u003e, 583-594.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/doi.org\/10.1016\/S0891-5849%2800%2900510-4\"\u003ehttp:\/\/doi.org\/10.1016\/S0891-5849(00)00510-4\u003c\/a\u003e\u003c\/p\u003e\n\u003ch6\u003eResearch\u003c\/h6\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003ch4\u003eFOOD SCIENCE: THE APPLICATION AND USE OF BLUEBERRY AND BLUEBERRY EXTRACT.*\u003c\/h4\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eBlueberry and Cognitive Support\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eBrewer, G.J., Torricelli, J.R., Lindsey, A.L., Kunz, E.Z., Neuman, A., Fisher, D.R., \u0026amp; Joseph, J.A. (2010). Age-related toxicity of amyloid-beta associated with increased pERK and pCREB in primary hippocampal neurons: reversal by blueberry extract.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eJ Nutr Biochem, 21\u003c\/em\u003e, 991-998. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.jnutbio.2009.08.005\"\u003e10.1016\/j.jnutbio.2009.08.005\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eCarey, A.N., Gomes, S.M., \u0026amp; Shukitt-Hale, B. (2014). Blueberry supplementation improves memory in middle-aged mice fed a high-fat diet.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eJ Agric Food Chem\u003c\/em\u003e,\u003cspan\u003e \u003c\/span\u003e\u003cem\u003e62\u003c\/em\u003e, 3972-3978. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1021\/jf404565s\"\u003e10.1021\/jf404565s\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eCasadesus, G., Shukitt-Hale, B., Stellwagen, H.M., Zhu, X., Lee, H.G., Smith, M.A., Joseph, J.A. (2004). Modulation of hippocampal plasticity and cognitive behavior by short-term blueberry supplementation in aged rats.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNutr Neurosci, 7\u003c\/em\u003e, 309-316. DOI:\u003ca href=\"https:\/\/doi.org\/10.1080\/10284150400020482\"\u003e10.1080\/10284150400020482\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eChemiack, E.P. (2012). A berry thought-provoking idea: the potential role of plant polyphenols in the treatment of age-related cognitive disorder.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eBr J Nutr, 108\u003c\/em\u003e(5), 794-800. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1017\/S0007114512000669\"\u003e10.1017\/S0007114512000669\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eDevore, E.E., Kang, J.H., Breteler, M.M., \u0026amp; Grodstein, F. (2012). Dietary intakes of berries and flavonoids in relation to cognitive decline.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eAnn Neurol\u003c\/em\u003e,\u003cspan\u003e \u003c\/span\u003e\u003cem\u003e72\u003c\/em\u003e(1), 135-43. DOI:\u003ca href=\"https:\/\/doi.org\/10.1002\/ana.23594\"\u003e10.1002\/ana.23594\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eDuffy, K.B., Spangler, E.L., Devan, B.D., Guo, Z., Bowker, J.L., Janas, A.M., Hagepanos, A., Minor, R.K., DeCabo, R., Mouton, P.R., Shukitt-Hale, B., Joseph, J.A., Ingram, D.K. (2008). A blueberry-enriched diet provides cellular protection against oxidative stress and reduces a kainate-induced learning impairment in rats.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNeurobiol Aging, 29\u003c\/em\u003e, 1680-1689. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2007.04.002\"\u003e10.1016\/j.neurobiolaging.2007.04.002\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eGoyarzu, P., Malin, D.H., Lau, F.C., Taglialatela, G., Moon, W.D., Jennings, R., Moy, E., Moy, D., Lippold, S., Shukitt-Hale, B., Joseph, J.A. (2004). Blueberry supplemented diet: effects on object recognition memory and nuclear factor-kappa B levels in aged rats.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNutr Neurosci, 7\u003c\/em\u003e, 75-83. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1080\/10284150410001710410\"\u003e10.1080\/10284150410001710410\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eJoseph, J.A., Shukitt-Hale, B., \u0026amp; Lau, F.C. (2007). Fruit polyphenols and their effects on neuronal signaling and behavior in senescence\u003cspan\u003e \u003c\/span\u003e\u003cem\u003e.\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003e\u003cem\u003eAnn NY Acd Sci\u003c\/em\u003e\u003cem\u003e, 1100,\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003e470-85\u003cem\u003e.\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003eDOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1196\/annals.1395.052\"\u003e10.1196\/annals.1395.052\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eJoseph, J.A., Shukitt-Hale, B., Denisova, N.A., Bielinski, D., Martin, A., McEwen, J.J., \u0026amp; Bickford, P.C. (1999). 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Flavonoids as therapeutic compounds targeting key proteins involved in Alzheimer's disease.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eACS Chem Neurosci, 5\u003c\/em\u003e(2), 83-92. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1021\/cn400213r\"\u003e10.1021\/cn400213r\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eCampos-Esparza, M.R., \u0026amp; Torres-Ramos, M.A. (2010). Neuroprotection by natural polyphenols: molecular mechanisms.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eCent Nerv Syste Agents Med Chem, 10\u003c\/em\u003e(4), 269-77. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/www.eurekaselect.com\/87028\/article\"\u003e10.2174\/187152410793429728\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eEsposito, E., Rotilio, D., Di Matteo, V., Di Giulio, C., Cacchio, M., Algeri, S. (2012). A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNeurobiol Aging, 23\u003c\/em\u003e, 719-735.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"http:\/\/doi.org\/10.1016\/S0197-4580%2802%2900078-7\"\u003ehttp:\/\/doi.org\/10.1016\/S0197-4580(02)00078-7\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eGalli, R.L., Bielinski, D.F., Szprengiel, A., Shukitt-Hale, B., Joseph, J.A. (2006). Blueberry supplemented diet reverses age-related decline in hippocampal HSP70 neuroprotection.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNeurobio Aging, 27\u003c\/em\u003e, 344-350. DOI:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2005.01.017\"\u003e10.1016\/j.neurobiolaging.2005.01.017\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eGao, X., Cassidy, A., Schwarzschild, M.A., Rimm, E.B., \u0026amp; Ascherio, A. (2012). Habitual intake of dietary flavonoids and risk of Parkinson disease.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNeurology, 78\u003c\/em\u003e(10), 1138-45. doi:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/dx.doi.org\/10.1212%2FWNL.0b013e31824f7fc4\"\u003e10.1212\/WNL.0b013e31824f7fc4\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eGiacalone, M., Di Sacco, F. Traupe, I., Topini, R., Forfori, F., \u0026amp; Giunta, F. (2011). Antioxidant and neuroprotective properties of blueberry polyphenols: A critical review.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNutr Neurosci, 14\u003c\/em\u003e(3), 119-25. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1179\/1476830511Y.0000000007\"\u003e10.1179\/1476830511Y.0000000007\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eFuentealba, J., Dibarrant, A.J., Fuentes-Fuentes, M.C., Saez-Orellana, F., Qunones, K., Guzman, L., … Aguayo, L.G. (2011). Syaptic failure and adenosine triphosphate imbalance induced by amyloid-β aggregates are prevented by blueberry-enriched polyphenols extracts.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eJ Neurosci Res, 89\u003c\/em\u003e(9), 1499-508. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1002\/jnr.22679\"\u003e10.1002\/jnr.22679\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eJoseph, J., Cole, G., Head, E., Ingram, D. (2009). Nutrition, brain aging, and neurodegeneration.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eJ. Neurosci.\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003e29(41), 12795–12801. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1523\/JNEUROSCI.3520-09.2009\"\u003e10.1523\/JNEUROSCI.3520-09.2009\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eJoseph, J.A., Denisova, N.A., Arendash, G., Gordon, M., Diamond, D., Shukitt-Hale, B., Morgan, D. (2003). Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNutr Neurosci, 6\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003e(3), 153-162. DOI:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/doi.org\/10.1080\/1028415031000111282\"\u003e10.1080\/1028415031000111282\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eJoseph, J.A., Shukitt-Hale, B., Denisova, N.A., Bielinski, D., Martin, A., McEwen, J.J., Bickford, P.C. (1999). 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DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.neurobiolaging.2006.05.031\"\u003e10.1016\/j.neurobiolaging.2006.05.031\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSpencer, J.P. (2010). Beyond antioxidants: the cellular and molecular interactions of flavonoids and how these underpin their actions on the brain.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eProc Nutr Soc, 69\u003c\/em\u003e(2):244-60. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1017\/S0029665110000054\"\u003e10.1017\/S0029665110000054\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSpencer, J.P., Vauzour, D., Rendeiro, C. (2009). Flavonoids and cognition: the molecular mechanisms underlying their behavioural effects. Arch Biochem Biophys, 492(1-2):1-9 DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1017\/S0029665112000146\"\u003e10.1017\/S0029665112000146\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSteward, M.N., Sridhar, A., \u0026amp; Meyer, J.S. (2013). Neural regeneration. Curr Top Microbiol Immunol, 367, 163-91. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1007\/82_2012_302\"\u003e10.1007\/82_2012_302\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eStrathearm, K.D., Yousef, G.G., Grace, M.H., Tambe, M.A., Ferruzzi, M.G., Wu, Q.L., Simon, J.E., Lila, M.A., \u0026amp; Rochet, J.C. (2014). Neuroprotective effects of anthocyanin-and proanthocyanidin-rich extracts in cellular models of Parkinson’s diseases.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eBrain Res\u003c\/em\u003e, 1555, 60-77. . DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.brainres.2014.01.047\"\u003e10.1016\/j.brainres.2014.01.047\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eStromberg, I., Gemma, C., Vila, J., Bickford, P.C. (2005). Blueberry- and spirulina-enriched diets enhance striatal dopamine recovery and induce a rapid, transient microglia activation after injury of the rat nigrostriatal dopamine system.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eExp Neurol, 196\u003c\/em\u003e, 298-307. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.expneurol.2005.08.013\"\u003e10.1016\/j.expneurol.2005.08.013\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSubash, S., Essa, M.M., Al-Adwi, S., Memon, M.A., Manivasagan, T., \u0026amp; Akbar, M. (2014). Neuroprotective effects of berry fruits on neurodegenerative diseases.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNeural Regeneration Research\u003c\/em\u003e, 9(16), 1557-1566. .\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/www.nrronline.org\/article.asp?issn=1673-5374;year=2014;volume=9;issue=16;spage=1557;epage=1566;aulast=Subash\"\u003eDOI:10.4103\/1673-5374.139483\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSweeney, M.I., Kalt, W., MacKinnon, S.L., Ashby, J., Gottschall-Pass, K.T. (2002) Feeding rats diets enriched in lowbush blueberries for six weeks decreases ischemia-induced brain damage.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNutr Neurosci 5\u003c\/em\u003e, 427- 431. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1080\/1028415021000055970\"\u003e10.1080\/1028415021000055970\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSzajdek, A., Borowska, J.E. (2008). Bioactive compounds and health-promoting properties of berry fruits a review.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003ePlant Foods Hum Nutr, 63\u003c\/em\u003e,147-156. DOI:\u003ca href=\"https:\/\/doi.org\/10.1007\/s11130-008-0097-5\"\u003e10.1007\/s11130-008-0097-5\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eWang, Y., Chang, C.F., Chou, J., Chen, H.L., Deng, X., Harvey, B.K., Cadet, J.L., Bickford, P.C. (2005). Dietary supplementation with blueberries, spinach, or spirulina reduces ischemic brain damage.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eExp Neurol, 193\u003c\/em\u003e, 75-84. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.expneurol.2004.12.014\"\u003e10.1016\/j.expneurol.2004.12.014\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eWilliams, C.M., El Mohsen, M.A., Vauzour, D., Rendeiro, C., Butler, L.T., Ellis, J.A., Whiteman, M., Spencer, J.P. (2008). Blueberry induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eFree Radical Biol Med, 45\u003c\/em\u003e, 295-305. DOI:\u003ca href=\"https:\/\/doi.org\/10.1016\/j.freeradbiomed.2008.04.008\"\u003e10.1016\/j.freeradbiomed.2008.04.008\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eWilliams, R.J. \u0026amp; Spencer, J.P. (2012). Flavonoids, cognition, and dementia: actions, mechanisms, and potential therapeutic utility for Alzheimer disease.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eFree Radic Biol Med, 52\u003c\/em\u003e(1), 35-45. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.freeradbiomed.2011.09.010\"\u003e10.1016\/j.freeradbiomed.2011.09.010\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eYoudim, K.A., Joseph, J.A. (2001). A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eFree Radic Biol Med, 30\u003c\/em\u003e, 583-594.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/doi.org\/10.1016\/S0891-5849%2800%2900510-4\"\u003ehttp:\/\/doi.org\/10.1016\/S0891-5849(00)00510-4\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eYoudim, K.A., Shukitt-Hale, B., Martin, A., Wang, H., Denisova, N., Bickford, P.C., Joseph, J.A. (2000). Short-term dietary supplementation of blueberry polyphenolics: beneficial effects on aging brain performance and peripheral tissue function.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNutr Neurosci, 3\u003c\/em\u003e, 383-397.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/dx.doi.org\/10.1080\/1028415X.2000.11747338\"\u003ehttp:\/\/dx.doi.org\/10.1080\/1028415X.2000.11747338\u003c\/a\u003e\u003c\/p\u003e\n\u003ch5\u003e\u003cem\u003e\u003cstrong\u003eSYSTEMIC ANTI-INFLAMMATORY SUPPORT\u003c\/strong\u003e\u003c\/em\u003e\u003c\/h5\u003e\n\u003cp\u003eAkiyama et al. (2000). Inflammation and Alzheimer’s disease.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNeurobiol Aging\u003c\/em\u003e, 21(3), 383-421. doi:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/dx.doi.org\/10.1101%2Fcshperspect.a006346\"\u003e10.1101\/cshperspect.a006346\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eGrace, M.H., Esposito D., Dunlap K.L., \u0026amp; Lila M.A. (2014). Comparative analysis of phenolic content and profile, antioxidant capacity, and anti-inflammatory bioactivity in wild Alaskan and commercial Vaccinium berries.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eJ Agric Food Chem\u003c\/em\u003e, 62(18), 4007-17. doi:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/dx.doi.org\/10.1021%2Fjf403810y\"\u003e10.1021\/jf403810y\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eMcAnulty, L.S. Nieman, D.C., Dumke, C.L., Shooter, L.A., Henson, D.A., Utter, A.C., … McAnulty, S.R. (2011). Effect of blueberry ingestion on natural killer cell counts, oxidative stress, and inflammation prior to and after 2.5 h of running.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eAppl Physio Nutr Metab\u003c\/em\u003e, 36(6), 976-84. DOI:\u003ca href=\"https:\/\/doi.org\/10.1139\/h11-120\"\u003e10.1139\/h11-120\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003ePanickar, K.S., \u0026amp; Anderson, R.A. (2010). Role of dietary polyphenols in attenuating brain edema and cell swelling in cerebral ischemia.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eRecent Pat CNS Drug Discov, 5\u003c\/em\u003e(2), 99-108. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.2174\/157488910791213149\"\u003ehttps:\/\/doi.org\/10.2174\/157488910791213149\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eYoudim, K.A., McDonald, J., Kalt, W., Joseph, J.A. (2002). Potential role of dietary flavonoids in reducing microvascular endothelium vulnerability to oxidative and inflammatory insults.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eJ. Nutr. Biochem,\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003e\u003cem\u003e13\u003c\/em\u003e(5), 282-288.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/doi.org\/10.1016\/S0955-2863%2801%2900221-2\"\u003ehttp:\/\/doi.org\/10.1016\/S0955-2863(01)00221-2\u003c\/a\u003e\u003c\/p\u003e\n\u003ch5\u003e\u003cem\u003e\u003cstrong\u003eBLUEBERRY AND HEART HEALTH\u003c\/strong\u003e\u003c\/em\u003e\u003c\/h5\u003e\n\u003cp\u003eErlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P… Jula, A. (2008). Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eAm J Clin Nutr 87\u003c\/em\u003e, 323-331.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/ajcn.nutrition.org\/content\/87\/2\/323.short\"\u003eArticle\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eLouis, X.L., Thandapilly, S.J., Kalt, W., Vinqvist-Tymchuk, M., Aloud, B.M, Raj, P., … Netticadan, T. (2014). Blueberry polyphenols prevent cardiomyocyte death by preventing calpain activation and oxidative stress.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eFood Funct, 5\u003c\/em\u003e(8), 1785-94. DOI:\u003ca href=\"https:\/\/doi.org\/10.1039\/c3fo60588d\"\u003e10.1039\/c3fo60588d\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eMcAnulty, L.S., Collier, S.R., Landram, M.J., Whittaker, D.S., Isaacs, S.E., Klemka, J.M… McAnulty, S.R. (2014). Six weeks daily ingestion of whole blueberry powder increases natural killer cell counts and reduces arterial stiffness in sedentary males and females.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNutr Res, 34\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003e(7), 577-84. 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(2015).A Review of the Cognitive Effects Observed in Humans Following Acute Supplementation with Flavonoids, and Their Associated Mechanisms of Action.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eNutrients\u003c\/em\u003e\u003cem\u003e,\u003cspan\u003e \u003c\/span\u003e\u003c\/em\u003e\u003cem\u003e7\u003c\/em\u003e(12), 10290-10306. doi:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/dx.doi.org\/10.3390\/nu7125538\"\u003e10.3390\/nu7125538\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eLila, M.A., Burton-Freeman, B., Grace, M., \u0026amp; Kalt, W. (2016). Unraveling Anthocyanin Bioavailability for Human Health.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eAnnu Rev Food Sci Technol,7\u003c\/em\u003e, 375-93. DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1146\/annurev-food-041715-033346\"\u003e10.1146\/annurev-food-041715-033346\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eMazza, G., Kay, C.D., Cottrell, T., \u0026amp; Holub, B.J. (2002). Absorption of Anthocyanins from Blueberries and Serum Antioxidant Status in Human Subjects.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eJ. Agric. Food Chem, 50\u003c\/em\u003e(26), 7731-7737.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jf020690l\"\u003ehttp:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jf020690l\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSandhu, A.K., Huang, Y., Xiao, D., Par, E., Edirisinghe, I., \u0026amp; Burton-Freeman, B. (2016). Pharmacokinetic Characterization and Bioavailability of Strawberry Anthocyanins Relative to Meal Intake.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eJ Agric Food Chem, 64\u003c\/em\u003e(24), 4891-9. DOI:\u003ca href=\"https:\/\/doi.org\/10.1021\/acs.jafc.6b00805\"\u003e10.1021\/acs.jafc.6b00805\u003c\/a\u003e\u003c\/p\u003e\n\u003ch6\u003eIngredients \u003c\/h6\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cspan\u003eOne Vegetarian Capsule Contains: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBlueberry (\u003cem\u003eVaccinium corymbosum\u003c\/em\u003e\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e) Freeze-dried Extract \u003c\/strong\u003e(80:1)  500mg \u003c\/span\u003e\u003cem\u003e\u003cbr\u003e\u003c\/em\u003e\u003cspan\u003e  Anthocyanins 12% Typical \u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e  Polyphenos 40% Minimum \u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e  Chlorogeninc Acid 5% Minimum \u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e  ORAC units per gram 6500 \u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eTypical Other Ingredients cellulose \u0026amp; water (capsule shell)\u003c\/span\u003e\u003c\/p\u003e\n\u003ch6\u003e\u003cspan mce-data-marked=\"1\"\u003eProtocol\u003c\/span\u003e\u003c\/h6\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cb\u003eBLUEBERRY EXTRACT\u003c\/b\u003e\u003cspan\u003e \u003c\/span\u003e— Designed to support the regeneration of the brain and nervous system\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eBrain health\u003c\/i\u003e: Take 1 capsule a day for regeneration of brain and nerve cells.*\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eCognitive and memory\u003c\/i\u003e: Take 1 capsule a day. Add 1 cap\u003cspan\u003e \u003c\/span\u003e\u003cb\u003eHigh ORAC\u003c\/b\u003e.  Students: Take 1-2 caps of both the Blueberry Extract and the High ORAC a day.*\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eFoggy brain\u003c\/i\u003e: Take 2 capsules for a month then 1 cap a day as maintenance.*\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eNeural regeneration\u003c\/i\u003e: Take 1-2 capsules a day. Add\u003cspan\u003e \u003c\/span\u003e\u003cb\u003ePhyto Power\u003c\/b\u003e\u003cspan\u003e \u003c\/span\u003eand\/or\u003cspan\u003e \u003c\/span\u003e\u003cb\u003eNo 7\u003c\/b\u003e\u003cspan\u003e \u003c\/span\u003efor broad-spectrum phenolic support.*\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eAnti-inflammation\u003c\/i\u003e: Due to the high concentration of anthocyanins (80 pounds produce 1 pound of the extract), the Blueberry Extract is excellent as anti-inflammatory agent. Reduces C-reactive protein (inflammatory marker), Isoprostane (marker for lipid oxidation), and NF-Kß (global inflammatory marker) for brain, heart, and DNA health.* \u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eOur Favorite\u003c\/i\u003e: When our president, Dr. Dohrea Bardell, went through her PhD program, for six years she took 2 capsules of the Blueberry Extract every day to keep her brain active and agile. She worked 12 hours days researching and writing. When she presented papers at conventions, she often added the\u003cspan\u003e \u003c\/span\u003e\u003cb\u003ePhyto Power\u003c\/b\u003e\u003cspan\u003e \u003c\/span\u003efor extra boost. The Blueberry Extract is one of her most favorite products.*\u003c\/p\u003e","brand":"BioImmersion Inc.","offers":[{"title":"Blueberry","offer_id":43712316112940,"sku":"TF008","price":141.98,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0576\/4779\/2172\/files\/Blueberry-Extract---Front.jpg?v=1723214870","url":"https:\/\/scoutside-sandbox.myshopify.com\/es\/products\/blueberry-extact","provider":"Scoutside Sandbox","version":"1.0","type":"link"}